The Convergence of Early-Life Stress and Autism Spectrum Disorder on the Epigenetics of Genes Key to the HPA Axis

TL;DR

This article addresses the intersection of early-life stress (ELS) and Autism Spectrum Disorder (ASD) through the lens of epigenetics, specifically fo

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The Facts

This article addresses the intersection of early-life stress (ELS) and Autism Spectrum Disorder (ASD) through the lens of epigenetics, specifically focusing on genes regulating the Hypothalamic-Pituitary-Adrenal (HPA) axis — the body's central stress response system. Emerging research suggests that adverse early-life experiences can produce lasting epigenetic modifications (such as DNA methylation and histone changes) that alter HPA axis gene expression, potentially contributing to or exacerbati

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Next Steps

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